More than 100 infected people in six of Melbourne's public housing towers will be offered hotel quarantine, as the Victorian government moves to stop further infection breakouts in the locked-down high-rise towers.

The move to offer hotel quarantine came as around 500 residents of one of the virus-affected public housing towers in 33 Alfred Street, North Melbourne, will remain in a hard lockdown for nine more days after testing revealed 53 cases of COVID-19.