Dr Khorshid said the AMA "is calling for a lockdown more Victorian in style, with very clear restrictions on what people can do to limit contact between people, between families and in particular to limit contact at work".
"What we do mean by this is we mean closing retail that is not essential.
That should not be up to common sense, not up to people doing the right thing but an edict from government to close non-essential retail," he added.
"It means closing non-essential businesses, as was done during the lockdown in Victoria…These measures are needed, they are not going to have a negative economic impact on Sydney because if they are not done, the economic impact on Sydney will be extraordinary.
"It is time to take this seriously, it is time to not be hesitant, do not be worried about how this might be perceived by the community.
"Take decisive action to address this crisis in Sydney and to give Sydney the best chance of getting out of this within weeks rather than months."