Warrego Highway closed in both directions after woman tragically killed in head-on crash

A woman has died despite the valiant efforts of witnesses who performed CPR on her for 30 minutes at the scene of a horror head-on crash between Toowoomba and Dalby.

ON SCENE: Paramedics and police are at the scene of a serious head-on collision along the Warrego Highway between Dalby and Toowoomba.

Despite the courageous efforts of bystanders to save her life, a woman has tragically died following a traffic crash in Bowenville.

Emergency services were called to the serious traffic crash involving two vehicles on the Warrego Highway near Bowenville Moola Connection Road at 4.56pm on Friday, a Queensland Police spokeswoman said.

NewsCorp understands bystanders performed CPR for 30 minutes in an attempt to save her life.

One adult and three children were taken to hospital, all in a stable condition.

Motorists have been told to avoid the Warrego Highway at Bowenville as the Forensic Crash Unit investigate, with the Highway closed in both directions.

A detour is in place via Jondaryan.

On Thursday morning, a 29-year-old woman and 12-year-old girl died following another crash in the Toowoomba region.

Initial investigations suggest a truck and SUV collided at Mount Irving just after 10am.

The man who was driving the SUV is fighting for life in hospital.