Ash Barty (1) v Lesia Tsurenko
The world No 1 was well beaten when they clashed in Brisbane a couple of years ago, but much has changed since. Expect the Roland Garros champion to start smoothly tonight. Picture: Getty Images | News Corp
Winner: Barty - 5-7, 6-1, 6-1

Andrew Harris v Matteo Berrettini (8)
The Australian has done well in lower-ranks and is a hard-working player. But the Italian announced himself as a rising star last year and reached the semi-finals of the US Open. It is a tough test for Harris. Picture: Getty Images | AP
Winner: Berrettini - 6-3, 6-1, 6-3

Sam Stosur v Caty McNally (Q)
Stosur is the reigning Australian Open doubles champion but is seeking her first singles win in Melbourne in five years. McNally qualified but is a significant talent who looks to have a very bright future. This is a tough one for the Australian. Picture: AP | Getty Images
Winner: McNally - 6-1, 6-4

Lizette Cabrera v Ann Li (Q)
The Queenslander is a promising player who was only narrowly beaten in a quarterfinal in Hobart last week by the eventual champion. She plays a qualifier here and will fancy her chances of making a solid start in Melbourne. Picture: Getty Images | Supplied
Winner: Ann Li - 7-6, 7-6

Jordan Thompson v Alexander Bublik
The Sydneysider is coming off a solid season where he established himself as a top 100 player. But he has suffered a couple of early season defeats and faces a challenge against Bublik, an emerging talent who has shown he may well become a top player. Picture: AFP
Winner: Thompson - 6-4, 6-3, 6-2

John Millman v Ugo Humbert
The Australian finished the season strongly to retain a place in the top 50 and has begun the year well. But so, too, has his rival. The Frenchman won a title in Auckland last week and will be full of confidence. Picture: Getty Images | AFP
Winner: Millman - 7-6, 6-3, 1-6, 7-5

Max Purcell v Jannik Sinner
It is great to see the young Australian work through qualifying to earn a spot in the Open. It shapes as a fascinating match, for Sinner is the most exciting teenager on tour. He underlined his quality when beating Àlex de Minaur to win the Next Gen Championships in Milan at the end of 2019. Picture: Getty Images
Winner: Sinner - 7-6, 6-2, 6-4

John-Patrick Smith v Guido Pella (22)
The veteran earned a spot when breaking through in the wildcard playoff last month. His reward is a clash with a seed, but he certainly has toughness and an ability to be tricky on court. Picture: AAP | AFP
Winner: Pella - 6-3, 7-5, 6-4

Marc Polmans v Mikhail Kukushkin
The Melburnian enjoyed a solid year at Challenger level but faces a test against a tour veteran who continues to perform at a high level on a yearly basis. Picture: AAP | AFP
Winner: Polmans - 6-4, 6-3, 4-6, 6-7, 6-4