Two drivers seriously injured after West Gate Freeway crash

A three-vehicle smash has left two drivers with serious injuries and closed a Melbourne freeway, causing major delays.

A major arterial road in Melbourne has been closed after a 4WD towing a horse float collided with a truck and a car.

The three-vehicle incident unfolded on the West Gate Fwy about 12.10pm on Saturday between Montague and Power Sts.

Police say the Montague St on ramp has been blocked and traffic is being diverted.

There are significant delays with multiple inbound lanes shut down. Picture: VicTraffic

Drivers of the 4WD and the car suffered serious injuries and have been taken to hospital, while the truck driver was not injured.

No animals were injured in the incident.

All inbound lanes between Montague St and the Burnley Tunnel have been closed, according to VicTraffic.

Drivers are being urged to use Montague St, City Rd and Power St or Kings Way and Dandenong Rd.

Inbown lanes of the West Gate have been closed. Picture: NewsWire / Luis Enrique Ascui

“The exact cause of the collision is yet to be determined at this stage,” a Victoria Police spokeswoman said.

“Anyone who witnessed the incident, has dashcam footage or with information is urged to contact Crime Stoppers.”