Christina Applegate hospitalised over 30 times with ‘unimaginable’ pain

Christina Applegate has shared the harrowing reality of her life, four years after receiving a shock diagnosis.

Christina Applegate revealed she has been hospitalised over 30 times for “unimaginable” pain from gastrointestinal issues amid her battle with multiple sclerosis.

During the one-year anniversary episode of her MesSy podcast with Jamie-Lynn Sigler, the Married … with Children star detailed her experience with the auto-immune disease after a listener wrote in that she was “throwing up and having diarrhoea every single day”.

“This is really important because for three years, since I was diagnosed, I’ve been in the hospital upwards of 30 times from throwing up and diarrhoea and pain that is unimaginable,” Applegate, 53, said on Tuesday’s show, reports Page Six.

“They’ve done every test known to man on me, put so much radiation into my body from CT scans to everything else,” she continued.

Applegate was diagnosed with MS in 2021. Picture: Matt Winkelmeyer/Getty Images

Applegate shared that she thinks she discovered the cause of her symptoms within the last month.

“Now, maybe this isn’t what’s happening, but I’m just gonna tell you this: Talk to your doctor about motility (gastrointestinal)) issues, OK? Because one of the things with MS is that it slows down our organs — not completely, but there is a slowing of the function of your organs,” the actress said.

Applegate further divulged that sometimes her body works doubble duty when she uses the bathroom.

“I’m gonna be really honest, if I have to poop, I puke. And when I puke, I get all the pain, and then all the things happen,” she said, calling the bodily response “the fight club”.

“So, there’s this really horrible argument,” Applegate explained. “It’s like everyone’s fighting with each other.”

She received a star on the Hollywood Walk of Fame in 2022. Picture: by Valerie Macon/AFP

However, the Bad Moms star said doctors have told her that the symptoms are unrelated to her MS.

But that hasn’t stopped Applegate from advocating for herself, including going in for a colonoscopy this week and having a “big conversation” with her medical team.

“There’s gotta be a correlation herenaid on the podcast.

The Sweetest Thing actress was diagnosed with MS in early 2021.

In March 2024, she revealed to People that she has to wear diapers “because you probably can’t get to the bathroom in time".

This article originally appeared in Page Six and was reproduced with permission.

Originally published as Christina Applegate hospitalised over 30 times with ‘unimaginable’ pain