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London lab prepares to pay volunteers to be infected with Covid-19 in world first

A London laboratory is preparing to pay volunteers thousands of dollars to be deliberately infected with Covid-19 in a world-first move.

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A London hotel repurposed into a lab is preparing to be the first in the world to infect humans with Covid.

The Whitechapel Hotel in the city’s East End is hosting a groundbreaking trial that took more than a year to be set up.

Volunteers prepared to see how they fare against the virus will be paid about £3000 to £4000 ($A5537 to $A7382) in a tax-free reimbursement.

They will stay in 19 rooms for about two weeks, complete with TVs and PlayStations to keep them entertained.

A hotel has been converted for the trial. Picture: Open Orphan
A hotel has been converted for the trial. Picture: Open Orphan

The former textile factory is now decked out with warning signs near the en suite rooms.

In the “living quarters” there are trolleys with swabs, vials and other equipment needed for monitoring the volunteers.

Viewing points have been installed in the bedroom doors so staff can check on the patients.

While the Covid trial is not yet running on humans – this is planned for next year – the facility is ready to go.

It is not just Covid that will be tested – people are being infected with other viruses and bacteria to see how they cope when put up against experimental vaccines or treatments.

Open Orphan is the company behind the groundbreaking research. Picture: Open Orphan
Open Orphan is the company behind the groundbreaking research. Picture: Open Orphan

The company behind it is Open Orphan – a small firm which announced plans to carry out a human challenge.

They are the only one to have conceived and got close to carrying out such a plan so far.

Cathal Friel, the company’s executive chairman, told The Telegraph: “The pandemic has been good to us.

“The world came flocking to our door, big pharma, small pharma, asking if we could help.”

The trial has involved isolating the virus from the “wild”, growing it in labs and producing it to a specific standard.

Volunteers will be paid thousands to participate. Picture: Open Orphan
Volunteers will be paid thousands to participate. Picture: Open Orphan

The old London building has had to have an entirely new level of biosecurity and is now fully transformed into a facility ready to test viruses.

Mr Friel started the company just over two years ago, initially as a pharma services business helping American drug developers to launch treatments for rare diseases in Europe.

The move is a world first. Picture: Open Orphan
The move is a world first. Picture: Open Orphan

He said: “Suddenly our small little niche business, which was doing one or two challenge studies a year, has started 10 this year.

“Next year it will do 15. The world has woken up to the fact that we need to restock the shelves with vaccines and antivirals.”

This article originally appeared on The Sun and was reproduced with permission

Original URL: https://www.news.com.au/world/coronavirus/health/london-lab-prepares-to-pay-volunteers-to-be-infected-with-covid19-in-world-first/news-story/9f635ec82e87cee6ad0d445618b40061