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Scientists could be close to discovering the secret to immortality, but would you really want to live forever?

SCIENTISTS could be close to discovering the secret to immortality. But it raises the question: how long do you really want to live for? 200 years? 10,000 years?

I RECENTLY sat down for what would become one of the toughest interviews I’ve ever done. It was on a topic which most people vacillate from complete denial to total dread: death.

I was beginning a report on how tech companies were tackling ageing when a question emerged: How long do I want to live? Any answer less than forever implies accepting death at some point.

The idea of accepting death for myself may be one thing, but accepting it for my children is a completely different thing. I was unprepared for how emotional it would be to ask my kids for their thoughts on our mortality.

Their answers — as thoughtful and sweet, as macabre and dark — launched me into a query that would lead me halfway around the world in search of answers from some of the most prominent voices and brightest minds leading the charge on human longevity. At the end of it all, no answers rang more true than those that set me on this journey in the first place, from the mouths of babes.

Josh Rushing interviewed his kids for a documentary that airs on SBS Dateline tonight.
Josh Rushing interviewed his kids for a documentary that airs on SBS Dateline tonight.

There are some who say that my kids may not have to face the ravages of getting old. Aubrey de Grey has gained quite a bit of notoriety from his TED talks about ageing. He’s built an entire persona as death’s naysayer.

He looks the part as well, wizard-like, with a greying Merlin-esque beard. “We have a completely, biologically invalid and incorrect idea that there is some kind of black and white wall between ageing itself — whatever we mean by that — and the diseases of old age, like Alzheimer’s, or cardiovascular disease or cancer.”

A simplified form of de Grey’s view is that ageing is a process in which our cells collect damage and, he believes it will soon be possible to not only slow that damage, but actually reverse it, leading to life eternal.

Aubrey de Grey and his impressive beard.
Aubrey de Grey and his impressive beard.

De Grey wraps his ideas in just enough science to obfuscate them from a laymen’s inquiry. When I expressed the conflict between my hope that his theories are correct and my journalistic scepticism, he replied, “Get a grip, grow up and stop thinking about whether you’re sceptical or you want hope. Just remember that you’re not a scientist yet and therefore, I know better than you.” It was less than confidence inspiring.

After meeting de Grey, it was easy to wonder if there’s much substance in the so-called longevity movement. But I found there are some very serious scientists, companies and investors who are working to extend our healthspan.

Google has started a company called Calico, which stands for the California Life Company. Its website sets out the mission, “Tackling ageing, one of life’s greatest mysteries.” We’re not sure how they intend to go about it as we couldn’t get them to give us an interview, but just the mere fact that Google has made a target of ageing has shifted the conversation about human longevity from the fringe with de Grey to the realm of the possible.

I’ve always been a fan of the poetry of Dylan Thomas and I couldn’t help but hear his poem, Do Not Go Gentle Into That Good Night, in the back of my head at each step of my journey:

Do not go gentle into that good night, Old age should burn and rave at close of day; Rage, rage against the dying of the light.

But I was also reminded of something Franz Kafka famously wrote, “The meaning of life is that it ends.” Aren’t death and life two sides of the same coin?

Then I met a jellyfish and karaoking scientist in a small seaside town in southern Japan, who challenged this very notion. In a cozy karaoke bar watching a scientist in a jellyfish costume perform original songs about his beloved jellyfish, I remember thinking that Dr. Shin Kabuto is an odd fellow and worrying that I had come halfway around the world to Shirahama, Japan, for someone who might be more character than substance.

Karaoke singing Jellyfish scientist Dr. Shin Kabuto.
Karaoke singing Jellyfish scientist Dr. Shin Kabuto.

In fact, Shin is the world’s leading expert on the Turritopsis Dornii jellyfish, more commonly known as the immortal jellyfish. These microscopic creatures have the unique ability to age as we do and then as their body starts to take on damage or trauma, they can reverse ageing and return to their polyp form before growing again.

Shin’s current crop of immortal jellyfish are on their 13th life.

The life cycle of Shin’s jellyfish.
The life cycle of Shin’s jellyfish.

While Shin is fascinated with the biological possibility of immortality, he’s not so seduced by it that he wishes for it for humanity. “Humans are not really thinking about nature or the environment at all and we are changing the earth in a way that suits our needs only. This isn’t really good, actually it’s really bad for the rest of the 1.4 million species that lives on earth. We are really making this a human-centric world.”

My interview with Shin, a biologist, turned surprisingly philosophical. But he was right, the idea of extending our lives may begin with science, but it leads to questions about the meaning of life and our place in this world.

Jellyfish scientist Dr. Shin Kabuto, when he’s not singing Karaoke.
Jellyfish scientist Dr. Shin Kabuto, when he’s not singing Karaoke.

For answers, I travelled to New Haven, Connecticut, and sat down with Shelly Kagan, who is the head of philosophy at Yale University. He teaches one of the most popular courses on campus. It’s called ‘Death’. A marketer, Shelly is not. Over the course of a semester, Shelly tries to teach his Ivy League students that, “death is really the end.”

“I think recognising that death is really the end implies the finitude of existence. And then that has the implication then that it really behoves you to think hard, long and hard about what is worth doing with your life,” he said.

Kagan’s tough-medicine approach to facing death may be philosophically valid, but that didn’t matter as I faced one of the toughest interviews of my career.

When I first asked my seven-year-old son Spencer how long he wanted to live, he said forever, so he could play video games for his whole life. Then, I walked him through the philosophical path of what forever actually means. Won’t you tire of playing video games? Do you really want to do that for 10,000 years?

So he changed his mind and decided that he no longer wanted to live forever. I wish I hadn’t done that. I was happier with his idea of an eternal Spencer. But, he’s right, the idea of living forever isn’t all it’s cracked up to be.

I think what I really want is for this moment in time with my five children at the ages they currently are-with my daughter who treats everyday like it’s a musical, and my two sons who would be happy as could be endlessly playing Minecraft together, and my oldest son trying to tackle the injustices in the world by going to law school and even my little baby who reaches with every part of his pudgy little body when he sees a small jar of smushed peas.

I want this moment with these extensions of my genome to last forever, and I’m afraid that’s something that no scientist or even mighty Google can help me with.

Josh Rushing said talking with his kids about immortality is the hardest interview he’s done.
Josh Rushing said talking with his kids about immortality is the hardest interview he’s done.

To see more, watch Dateline tonight, 9.30pm on SBS.

Follow Josh Rushing on Twitter @joshrushing

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Original URL: https://www.news.com.au/technology/science/human-body/scientists-could-be-close-to-discovering-the-secret-to-immortality-but-would-you-really-want-to-live-forever/news-story/dc00f07e66baf026319957ab9b44a86e