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Fourth Covid-19 booster ‘not good enough’ against Omicron, Israeli study finds

An Israeli study has found even a fourth dose of a Covid-19 vaccine is “not good enough” to prevent Omicron infection.

Prime Minister Morrison discusses Australia's booster dose figures

Even a fourth shot of a Covid-19 vaccine is “not good enough” to prevent Omicron, according to a preliminary study in Israel.

Sheba Hospital last month tested a fourth shot given to more than 270 medical workers, with 154 getting the Pfizer jab and 120 receiving Moderna.

The researchers revealed on Monday that both groups showed a “slightly higher” increase in antibodies than after the third shot — but still not enough to prevent Omicron, the latest variant responsible for the vast majority of infections around the world, the NY Post reports.

“Despite increased antibody levels, the fourth vaccine only offers a partial defence against the virus,” said Dr Gili Regev-Yochay, director of the hospital’s infection disease unit leading the study.

The study saw “many infected with Omicron who received the fourth dose,” she said. “Granted, a bit less than in the control group, but still a lot of infections.

The Israeli study found groups given a fourth vaccine dose showed a ‘slightly higher’ increase in antibodies than after the third shot — but still not enough to prevent Omicron. Picture: Jack Guez/AFP
The Israeli study found groups given a fourth vaccine dose showed a ‘slightly higher’ increase in antibodies than after the third shot — but still not enough to prevent Omicron. Picture: Jack Guez/AFP

“The vaccines, which were more effective against previous variants, offer less protection versus Omicron.”

Dr Regev-Yochay added the vaccines were “not good enough” to prevent the less-severe new variant.

The findings have not yet been published and do not reveal specific data.

But the study raised questions about Israel’s decision to be the first in the world to offer a second booster shot — and fourth overall — to its over-60 population.

The government says over 500,000 people have received the second booster in recent weeks. But the country has still seen record-high infections recently, even though 80 per cent of Israel’s adult residents have received two shots and more than half have gotten boosted.

Hours after releasing the results, Sheba Hospital called for “continuing the vaccination drive … even though the vaccine doesn’t provide optimal protection against getting infected with the variant.”

Israel has started administering fourth Covid vaccine shots to people over 60 and health workers amid a surge driven by the Omicron variant. Picture: Jack Guez/AFP
Israel has started administering fourth Covid vaccine shots to people over 60 and health workers amid a surge driven by the Omicron variant. Picture: Jack Guez/AFP

Hebrew media reported that the hospital was pressured into issuing that statement after the Health Ministry didn’t like the study’s results, according to the Times of Israel.

Dr Nahman Ash, director of Israel’s Health Ministry, also insisted the findings did not mean the fourth-shot effort was a mistake.

“It returns the level of antibodies to what it was at the beginning of the third booster. That has great importance, especially among the older population,” he told Channel 13 TV.

On Tuesday, the Israeli government said it was shortening the mandatory quarantine period from seven days to five days in order to help keep the economy running.

“This decision will enable us to continue safeguarding public health on the one hand and to keep the economy going at this time on the other, even though it is difficult, so that we can get through this wave safely,” Prime Minister Naftali Bennett said.

This article originally appeared on NY Post and was reproduced with permission

Read related topics:Vaccine

Original URL: https://www.news.com.au/technology/science/human-body/fourth-covid19-booster-not-good-enough-against-omicron-israeli-study-finds/news-story/29e363a5f80e67245175cc98bdc0952d