Political pundits are obviously having their say on the debate, but before we get to them, let's hear what some undecided voters thought.
Republican pollster Frank Luntz ran a focus group during the event, and its participants preferred Mike Pence to Kamala Harris – though they were not particularly impressed by either candidate.
"The complaint about Kamala Harris was that she was abrasive and condescending. The complaint about Mike Pence was that he was too tired, but vice presidential or presidential," Luntz told Fox News.
"If this is a battle of style over substance, which is often the case with undecided voters – they simply do not choose on policy, they choose on persona – this was Mike Pence's night.
"I want to emphasise it's not that Pence did so well, because they felt both candidates were not answering the questions as well as they would have liked.
"They were more upset with Kamala Harris's reactions to Pence – the smiling, the smirking, the scowling. They were angier at that than they were that Mike Pence went over his time in almost every answer."
Ms Harris certainly was more expressive than Mr Pence in terms of her facial expressions, partly because the Vice President barely moves any of his facial features. Ever. It's one of his more fascinating traits.
OK, on to the pundits.
Over on ABC News, Martha Raddatz defended Mr Pence from the accusation that he interrupted Ms Harris too often and "mansplained" to her.
"When I hear people talk about mansplaining and talk about these things with Kamala Harris, and a man shouldn't interrupt her and it's going to look bad – Kamala Harris is a vice presidential candidate. She should be able to stand up for herself," Raddatz said.
"Yes, you can talk about her history, and who she is, and she's a woman of colour there. But a man can interrupt another vice presidential candidate. It is up to that candidate to talk back, to interrupt themselves, or hold on to that debate in any way they could."
On CNN, liberal commentator Van Jones offered the complete opposite point of view, labelling Mr Pence the "mansplainer-in-chief".
Jones argued Ms Harris had cleared the most important bar in front of her, and now "nobody is saying she could not be president".
"She cleared that bar. It is off the table," he said.
And on MSNBC, former Republican political operative Nicolle Wallace – a vehement critic of Donald Trump – said the debate would probably have no effect on the race.
"The only time these debates have mattered are when the presidential candidate has stumbled dramatically," Wallace said.
She cited the vice presidential debates from 2004, which came after a very weak performance by George W. Bush the week before, and 2012, when Mitt Romney had toweled up Barack Obama the week before Joe Biden took the stage.
"This could have mattered. I don't think it did," she continued.
"The problem tonight is that Mike Pence appeared flaccid and anemic, and that will hurt him with men.
"I think there are going to be questions if he is not feeling that great after this performance. The only time he came to life is when he prosecuted Senator Harris for not answering his question (on the Supreme Court), and he didn't respond in full to a single question from the moderator.
"This is not what they (the Trump campaign) needed. He had to look presidential tonight, and he just looked limp and lame."
You can find some more reaction to the debate here.
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