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10 Best Peptide Serums to Help Improve Your Skin in 2025

We’ve discovered the Hailey Bieber approved beauty hack that’s designed to give you bouncy skin.

These are the best peptide serums on the market.
These are the best peptide serums on the market.

These products are hand-picked by our team to help make shopping easier. We may receive payments from third parties for sharing this content and when you purchase through links in this article. Product prices and offer details are not assured, and should be confirmed independently with the retailer. Learn more

While we can all agree ageing is a privilege, there are some mornings where we want our skin to look just that little bit more plump and bouncy.

Enter a peptide serum.

The latest craze in the beauty world by storm, peptides are short chains of amino acids that are commonly used to support the function of your skin barrier and increase overall hydration.

“Think of them as the building blocks of proteins like collagen and elastin, which are essential for firm, youthful-looking skin,” says Daniel Isaacs, Chief Product Officer at Medik8.

Even Hailey Bieber is a fan.

“I really, really love peptides for the skin, I think that it’s one of the best ingredients to use”, she told Glamour.

So much so, that she created the TikTok-viral Rhode Skin Peptide Glazing Fluid.

While we can’t get our hands on it in Australia just yet, here are some more peptide serums you can use to help get Hailey’s incredible skin – including one that delivers “instant results” for plump and bouncy skin.


OUR TOP PICKS


EDITOR’S PICKS: BEST PEPTIDE SERUMS

Medik8 Liquid Peptides Advanced MP, $160 at Adore Beauty

Why we love it: Offers a clinically proven formula that feels lightweight and gentle on the skin.

What to consider: High price tag.

Formulation: Serum | Size: 30ml | Best for: All skin types, especially those with mature skin

Tried and Tested by Stephanie Yip, eCommerce Travel Writer

As I boldly head into my 40s, wrinkles, fine lines and expression lines have begun to creep across my face at what feels like lightning speed. Yup, once you’ve seen them, it’s hard to unsee them. So in an attempt to slow things down, I’ve upped my beauty routine to include Medik8’s new Liquid Peptides Advanced MP.

Packed with Dual Mini Proteins, this pocket rocket aims to gently relax and smooth lines within minutes, and plump up skin by boosting its collagen, elastin and hyaluronic acid levels over a few weeks.

Obviously the sceptic in me took this with a grain of salt, but truly the effects were almost instantaneous and, after three weeks, my eye wrinkles have flattened out and my self confidence is through the roof.

On top of the results, I love how light and fast absorbing the serum is and that it’s scent free, so it works well with the rest of my skincare routine.

I’m now actively using it to target a pesky frown line that’s been bothering me for years and I’m confident that it’ll be hardly noticeable in a few weeks.

See the dramatic before and after of Stephanie's under eye area. Picture: Stephanie Yip
See the dramatic before and after of Stephanie's under eye area. Picture: Stephanie Yip

SHOP HERE

Paula’s Choice Pro-Collagen Multi-Peptide Booster, $89 at Sephora

Why we love it: The lightweight and silky formula feels great on the skin.

What to consider: High price tag for the little product you get.

Formulation: Serum | Size: 20ml | Best for: All skin types

Tried and Tested by Marina Tatas, Senior Shopping Writer

I’ve gone through a few bottles of this stuff and let me tell you, it is liquid gold. The Pro Collagen Multi Peptide Booster from Paula’s Choice is one of the most hydrating, soothing and repairing serums I’ve ever tried. Formulated with a bunch of – you guessed it – peptides, this lightweight and silky serum works almost instantly and absorbs quickly. One thing I will say, I feel as if the dropper can be improved – the serum is almost a little too thick and can sometimes get stuck in the dropper but besides that, I am truly obsessed.

SHOP HERE

Olay Super Serum Night Repair, $69.99 at Priceline

Why we love it: Olay’s Super Serum offers five benefits in one.

What to consider: May feel too strong for super sensitive skin types.

Formulation: Serum | Size: 30ml | Best for: All skin types

What You Need To Know

If you’re looking for a multipurpose peptide serum, Olay’s Super Serum is the way to go.

It’s packed with five potent ingredients that work hard while you sleep – peptides, niacinamide, glycerin, lactic acid and salicylic acid.

Expect to see a brighter and more hydrated complexion, as it helps to diminish signs of ageing and make sure your skin look more even and balanced.

With a lightweight and fast absorbing texture, this is the kind of serum you can use every night with no issue.

SHOP HERE


BEST K-BEAUTY PEPTIDE SERUM

COSRX 6X Peptide Collagen Booster Toner Serum, $34 (down from $44.99) at Amazon Australia

Why we love it: This a toner and serum hybrid that feels super lightweight on the skin.

What to consider: Some users did not see a massive difference from using this product.

Formulation: Essence | Size: 150ml | Best for: All skin types

What You Need To Know

The COSRX 6X Peptide Collagen Booster Toner Serum is our top pick when it comes to K-Beauty skincare. It’s been named the “best serum ever” by almost 5000 five-star reviewers on Amazon, with another happy shopper claiming it leaves their skin looking “smooth and radiant”.

Due to its hybrid formulation, its recommended to use the COSRX toner serum as the first step of your skincare routine. Packed with six peptides, this will work hard to hydrate the skin and boost the rest of the products you choose to apply over the top.

It’s also got niacinamide, adenosine, hyaluronic acid and allantoin to hydrate, even out your skin and overall improve the look of fine lines.

SHOP HERE


BEST BUDGET-FRIENDLY PEPTIDE SERUM

Advanced Clinicals Peptide Serum, $16 at iHerb

Why we love it: Budget-friendly price tag.

What to consider: Can sometimes be hard to get your hands on.

Formulation: Serum | Size: 52ml | Best for: All skin types

What You Need To Know

If you’re shopping on a budget, the Advanced Clinicals Peptide Serum is a winner for under $20. Featuring loads of different peptides to hydrate the skin and make it appears softer and smoother.

It’s also racked up over 10k five-star ratings on iHerb, with rave reviewers claiming this serum “works wonders” for “smooth and hydrated skin”.

SHOP HERE

BOOST LAB Multi-Peptide Anti-Ageing Serum, $29.95 at Priceline

Why we love it: Low price tag and also great for sensitive skin.

What to consider: Some users claim the serum can pill when used with other products.

Formulation: Serum | Size: 30ml | Best for: All skin types

What You Need To Know

Another potent peptide serum for under $30 is this pick from BOOST LAB. Suitable for daily use and targeting visibly signs of ageing, the serum is formulated with pollustop, natural plant sugars and peptides.

It’s also picked up great five-star ratings on the Adore Beauty website, with happy shoppers calling it a “hidden gem” and commenting that they “wake up with glowing and fresh skin”.

SHOP HERE


BEST PEPTIDE SERUM FOR MATURE SKIN

Skinstitut EXPERT Reset Skin-Firming Peptide Serum, $99 at Adore Beauty

Why we love it: This is a multi-tasking serum that targets multiple signs of ageing.

What to consider: High price tag.

Formulation: Serum | Size: 30ml | Best for: Mature skin types

What You Need To Know

It’s formulated with a firma-peptide complex, niacinamide, panthenol, kakadu plum extract and hyaluronic acid – all working together to harmoniously to make your skin feel more hydrated and look more plump and bouncy.

The ultra-lightweight texture easily absorbs into the skin, working well either morning or night.

Five-star rating Adore Beauty shoppers claim it leaves their dry skin looking “super glowy”.

SHOP HERE

Multi-Peptide + Copper Peptides 1% Serum, $54.10 at The Ordinary

Why we love it: Great for those looking to target advanced signs of ageing.

What to consider: Some users report the serum bottle leaks on them.

Formulation: Serum | Size: 30ml | Best for: Mature skin types

What You Need To Know

This advanced serum from The Ordinary is formulated with 1 per cent copper peptides, and these help to support the skin’s natural renewal process, as well as a bunch of antioxidants to boost the look of your skin.

From over 600 five-star ratings on The Ordinary, happy shoppers claim its “very gentle and lightweight” and makes their skin look “super glowy”.

SHOP HERE


BEST PEPTIDE SERUM FOR DRY SKIN

The Ordinary Multi-Peptide + HA Serum, $52.60 at Myer

Why we love it: Perfect for those looking for a peptide serum that can also address dry skin issues.

What to consider: Nothing we can fault.

Formulation: Serum | Size: 60ml | Best for: Dry skin types

What You Need To Know

This is the kind of peptide serum that can do a bit of everything. Not only do the five peptide technologies help to make your skin look more plump, but the addition of hyaluronic acid helps to give it that bounce.

It’s been named a “skincare essential” by five-star rating Myer shoppers.

Another commented, “this serum is lightweight and absorbs so easily into my skin. Its so hydrating and makes my skin glow. Love this product!”

SHOP HERE


BEST PEPTIDE SERUM FOR OILY SKIN

BUBBLE Water Slide Hyaluronic Acid + Peptides Hydration Boosting Serum, $29 at Priceline

Why we love it: An amazing hydrating serum for oily skin types.

What to consider: Some users felt it didn’t make a big difference to their skin.

Formulation: Serum | Size: 30ml | Best for: Oily skin types

What You Need To Know

While you may not suspect this hydrating peptide-filled serum to be targeted towards oily skin types, it’s the addition of one ingredient that really changes the game – niacinamide.

Not only does niacinamide boost skin barrier function, but it also helps to control oil and balance the skin. Pair that with hyaluronic acid and a blend of peptides, and you’ve got a universally hydrating serum – that’s also priced at under $30.

It’s even racked up an impressive average rating of 4.9 out of five on the Priceline website.

SHOP HERE


WHAT TO LOOK FOR WHEN BUYING A PEPTIDE SERUM

When choosing peptide serums to include in our list, we evaluated several factors:

Budget: You don’t need to break the bank to find a potent peptide serum. We’ve got picks on our list for as little as $16.

Skin type: Your skin type can influence the kind of peptide serum you choose to buy. If you have oily skin, avoid anything filled with heavy oils. And if you have dry skin, looking for hydrating ingredients like hyaluronic acid and glycerin.

Added ingredients: While a peptide serum works great on its own, you can look for a serum with added ingredients to reap even more benefits.


HOW WE CHOOSE PRODUCTS

With hundreds of serums available, it’s impossible to test every product out there. In our search for the best peptide serums, we read hundreds of customer reviews and looked at test results and ratings from product review sites to find the best one for you.

We also spoke to Daniel Isaacs, Chief Product Officer and Founding Partner of Medik8, to figure out why our skincare routine could benefit from adding a peptide serum.


FREQUENTLY ASKED QUESTIONS

DO PEPTIDE SERUMS ACTUALLY WORK?

Yes – like anything, if you use them consistently in your skincare routine, you’ll see great results.

Daniel explains, “peptides have always been a cornerstone of this approach due to their ability to deliver transformative results while working harmoniously with the skin. They are an essential ingredient for maintaining youthful, radiant skin.”

HOW LONG DOES IT TAKE TO SEE RESULTS FROM USING A PEPTIDE SERUM?

“Consistency is key with all skincare but some peptide products can help your skin start to show results with their key benefits within weeks, but long-lasting visible results will take 6-12 weeks,” Daniel shares.

WHAT MAKES MEDIK8’S LIQUID PEPTIDES ADVANCED MP DIFFERENT TO OTHER PEPTIDE SERUMS ON THE MARKET?

It all comes down to the formula, and that’s why the Liquid Peptides Advanced MP is our top pick for peptide serums.

“Our breakthrough Dual MiniProteins are highly powerful like a peptide and potent like a protein. But the key is their shrunken size, which enables them to best penetrate the skin.”

He continues, “think of them as small, but mighty in their ability to target cells that need them most to smooth and firm the skin for rapid wrinkle reduction.”


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Marina Tatas
Marina TatasSenior Shopping writer

Marina has been helping Aussie shoppers spend their hard-earned cash wisely for almost seven years. She's the news.com.au checkout team's expert in sales and deals, covering major sales events like Black Friday and Boxing Day for the past six years. Marina is also passionate about all things beauty and there’s nothing she loves more than trialling and testing new beauty products - moisturisers, serums, creams, you name it. She has previously worked at comparison site Finder and has written for popular titles including Marie Claire and The Carousel.

Original URL: https://www.news.com.au/checkout/beauty/skincare/serums-and-oils/best-peptide-serums/news-story/1f8a6adc951fe7ffb8aa124769d13c7b