And that is that. South Africa win by six wickets with 124 balls remaining, with David Miller hitting the winning runs with his first ball faced.
A truly crushing victory to draw first blood in the three-game series.
Their quicks set things up with a devastating display in the opening hour – Dale Steyn led the way with two early wickets. Ngidi was also extremely impressive, finishing with two wickets himself before Phehlukwayo ripped the Australian middle order to pieces with three wickets.
Australia's total of 152 was never going to be enough and despite a three-wicket effort from Marcus Stoinis, Australia were well and truly outplayed.
Quinton de Kock top-scored in South Africa's runchase, hitting 47 from 40, while Hendricks played a patient knock – scoring 44 from 74.
Aidan Markram also looked impressive adding 36 from 32.
We move on to Adelaide, where Australia will seek to level the best-of-three series on Friday.